Opto-/Chemogenetic


CAV PRS HA-hM4D(Gi)


An E1/E3-deleted, replication-defective, CAV-2 vector harbouring the PRS promoter that leads to the expression in noradrengenic neurons of hM4D(Gi) with an HA tag in N-Ter. The open reading frame is followed by an hGH polyA signal. Cassette is derived from plasmid #121538, Addgene.

CAV-2Opto-/ChemogeneticPRS promoter

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CAV PRS hM3D(Gq)-mCherry


An E1/E3-deleted, replication-defective, CAV-2 vector harbouring PRS promoter that leads to hM3D(Gq) fused to mCherry expression in noradrengenic neurons. The open reading frame is followed by an SV40 polyA signal. The vector was generated by the Pickering Lab (Bristol, UK).

CAV-2Opto-/ChemogeneticPRS promoter

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CAV PRS DIO hM4D(Gi)-mCherry


An E1/E3-deleted, replication-defective, CAV-2 vector harbouring the PRS promoter that leads to a Cre-dependent hM4D(Gi) fused to mCherry expression in noradrengenic neurons. The open reading frame is followed by an hGH polyA signal. Cassette derived from plasmid #44362, Addgene.

CAV-2Cre-inducibleOpto-/ChemogeneticPRS promoter

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CAV PRS stGtACR2-FRed


An E1/E3-deleted, replication-defective, CAV-2 vector harbouring PRS promoter that leads to soma-targeted Guillardia theta anion-conducting channelrhodopsin 2 fused to FusionRed FP expression in noradrengenic neurons. The open reading frame is followed by an SV40 polyA signal.

CAV-2Opto-/ChemogeneticPRS promoter

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CAV hSyn DIO hM3D-mCherry


An E1/E3-deleted, replication-defective, CAV-2 vector harbouring the hSyn promoter that leads to a Cre-dependent hM3Dq fused to mCherry expression. The open reading frame is followed by an hGH polyA signal. Cassette derived from plasmid #44361, Addgene.

CAV-2Cre-inducibleOpto-/Chemogenetic

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CAV hSyn DIO hM4D-mCherry


An E1/E3-deleted, replication-defective, CAV-2 vector harbouring the hSyn promoter that leads to a Cre-dependent hM4Di fused to mCherry expression. The open reading frame is followed by an hGH polyA signal. Cassette derived from plasmid #44362, Addgene.

CAV-2Cre-inducibleOpto-/Chemogenetic

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CAV hM3D IRES mCitrine


An E1/E3-deleted, replication-defective, CAV-2 vector harbouring the CMV promoter that leads to hM3D (DREADD) and mCitrine expression. The open reading frame is followed by an SV40 polyA signal.

CAV-2Opto-/Chemogenetic

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CAV DIO hM4D-mCherry


An E1/E3-deleted, replication-defective, CAV-2 vector harbouring the CMV promoter that leads to Cre-inducible hM4D (DREADD) fused to mCherry expression. The open reading frame is followed by an SV40 polyA signal.

CAV-2Cre-inducibleOpto-/Chemogenetic

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